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Palliative care Dysphagia

Dysphagia can be defined as the difficulty in transferring the alimentary bolus (liquid or solid) from the mouth to the stomach.

In a palliative care unit (like St Christopher), dysphagia is observed in approximately 10% of patients (however, the unit also welcomes patients with lateral sclerosis for which dysphagia is an evolutive phase of the disease).

Deglutition physiology

Four steps are necessary for correct swallowing:

endobuccal preparation of the alimentary bolus (mastication, salivation),

oral swallowing phase, with closed lips and anterior tongue retraction pushing the bolus towards the oropharynx,

pharyngeal phase: partial occlusion of the nasal fossa, complete occlusion of larynx, stopped breathing,

esophageal phase: peristalsis pushes the bolus towards stomach.

The first two phases are voluntary; the latter two are reflexive.

Pathophysiology of deglutition disorders

A tumour mass in the mouth or the superior pharynx will rapidly lead to swallowing difficulties, whereas a low pharynx tumour or an oesophageal tumour will be troublesome only when voluminous.

Treatment of the tumour also provokes major swallowing side-effects:

surgery,

radiotherapy: post-radiotherapy sclerosis, mouth dryness, candidiasis,

chemotherapy, not onlyvia chemotherapy alone, but also through the increased risk of candidiasis complicating dry irradiated mucosa,

other potential mouth infections: herpes zoster, cytomegalovirus.

Major problems

Depending of the location, patients may suffer from:

mouth leakage (the patient slavers): lip sensation disorders, abnormal tongue movement, reduced swallowing reflex,

frequent nasal regurgitations poor palatal function (often after surgery or radiotherapy),

swallowing difficulty: the patients pushes his head backwards in order to swallow,

coughing when swallowing may occur

Therapeutic attitude

Should enteral alimentation (feeding) or parenteral alimentation (hydration) be proposed to the patient?

The following table summarises enteral and parenteral feeding indications:

General indications
Parenteral route
Nasogastric tube,
gastrostomy
Indications

Swallowing time greater than 10 seconds

No improvement after rehabilitation or nutritional support

Radical treatment proposed (surgery, radiotherapy)

Indications

Complete pharyngeal or oesophageal obstruction

Short use (a few weeks),

Other intestinal or gastric problems

Indications

Prolonged use (more than two weeks)
Contraindications



Rapid terminal deterioration

Other major difficulties

Contraindications



Presence of sepsis

Difficulties at home

No access to biochemical monitoring

No access to nutritional team

Superior vena cava compression

Contraindications

For the tube: oesophageal obstruction, fistula



For gastrostomy: gastric tumour, occlusion

Some simple advice may help a dysphagic patient to eat normally by mouth:

Palliative care in cancer - You are looking at www.oncoprof.net website