Zoledronate (Zometa™) is exclusively administered intravenously.

Its indications are :


Since it is slowly eliminated from the blood, the usual dosage is relatively low (about 4 to 8 mg per cure which can be renewed every 4 weeks). In malignant hypercalcaemia, strict monitoring is required. Infusion is short (about 30 minutes).

During infusion, fever may be observed (delayed fever can also occur ) as well as flu-like syndrome, local reactions, bone pains, myalgias. All of these side effects are generally mild.

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