Ch 6 Example of Cancer Classification
Cancer
Classification
Urinary bladder cancer
 

The following diagrams can be consulted:

The clinical staging of bladder carcinoma is determined by the depth of invasion of the bladder wall by the tumour. This determination requires a cystoscopic examination that includes a biopsy, and examination under general anaesthesia to assess the size and mobility of palpable masses, the degree of induration of the bladder wall, and the presence of extravesical extension or invasion of adjacent organs

T Criterion

Classification Description
TX Primary tumour cannot be assessed
T0 No evidence of primary tumour
Tis Carcinoma in situ (i.e., flat tumour)
Ta Noninvasive papillary carcinoma
T1
Tumour invading subepithelial connective tissue
T2 Tumour invading bladder muscle
T2a
Tumour invading superficial muscle (inner half)
T2b Tumour invading deep muscle (outer half)
T3    Tumour invading perivesical fat tissue
T3a
Microscopically
T3b Macroscopically (extravesical mass)
T4 Tumour invading neighbouring organs
T4a
Tumour invading the prostate, uterus, vagina
T4b
Tumour invadin the pelvic wall, abdominal wall

N Criterion

Classification
Description
NX Regional lymph nodes cannot be assessed
N0
No regional lymph node metastasis
N1
Metastasis in a single lymph node, <=2 cm at largest point
N2
Metastasis in a single lymph node, >2 cm but <=5 cm at largest point; or multiple lymph nodes, <=5 cm at largest point
N3
Metastasis in a lymph node, >5 cm at largest point

Therapeutic results

Stage 5 year survival
Tis > 90%
T1
75%
T2
60%
T3a
50%
T3b
15%
N+
<5%
M1
< 5%

For French speaking readers, the Lorraine oncology network website, Oncolor is an interesting website which describes classifications and therapeutic attitudes for superficial or infiltrating tumours.

For English speaking readers, the NCI website is of great interest.

 
Cancer Classification - You are looking at www.oncoprof.net website