Ch 6 Example of Cancer Classification
Cancer
Classification
Vocal Cord Cancer 

The following table gives a general outline of vocal chord cancer classification.

Diagrams are available for the following:

T Classification

Classification

Description

T1


T1a
T1b

Tumour limited to the vocal chord(s) (may involve anterior or posterior commissure) with normal mobility

  • tumour limited to one vocal chord
  • tumour involves both vocal chords
Tumour extending to supraglottis and/or subglottis and/or with impaired vocal chord mobility
Tumour limited to the larynx with vocal chord fixation and/or invading paraglottic space, and/or minor thyroid cartilage erosion (e.g., inner cortex)
T4

T4a




T4b

T4 : extension beyond the larynx

T4a: tumour invading through the thyroid cartilage and/or invading tissues beyond the larynx (e.g., trachea, soft tissues of neck, including deep extrinsic muscle of the tongue, strap muscles, thyroid, or oesophagus)

T4b: tumour invading prevertebral space, encasing carotid artery, or invading mediastinal structures

N Classification

N.B. on the following link you will find the anatomy of cervical nodes.

Classification

Description

NX Regional lymph nodes cannot be assessed
NO No regional lymph node metastasis
N1 Metastasis in a single ipsilateral lymph node, 3 cm or less at its largest point
Metastasis in a single ipsilateral lymph node larger than 3 cm but no more than 6 cm at its largest point
Metastasis in multiple ipsilateral lymph nodes, no larger than 6 cm at its largest point
Metastasis in bilateral or contralateral lymph nodes, no larger than 6 cm at its largest point
Metastasis in a lymph node more than 6 cm at its largest point

Usual therapeutic results

Supra glottic tumour
T
Local control
5 year survival
T1
80-90%
65-90%
T2
60-80%
50-65%
T3
35-70%
35-55%
T4
30-60%
15-40%

It is clear that despite more and more mutilating surgery, 5 year survival diminishes: this is due to the high frequency of remote metastases (and of monstrous nodes which cannot be cured by radiotherapy).

Vocal chord tumour
T
Local control
5 year survival
T1
85-95 %
80-95 %
T2
65-75 %
60-85 %
T3
20-35 %
35-60 %
T4
15-30 %
10-30 %

Compilation of results according to Laramore (Radiation therapy of Head and Neck Cancer. Berlin. Springer Verlag 1988).

For French speaking readers : the website of Lorraine Region network, Oncolor, about larynx tumours (in particular the discussion on larynx conservation) is a very interesting website about the decision tree in larynx carcinoma.

For English speaking readers, the National Cancer Institute describes Lip and Oral Cavity Cancer with classification and treatment options.

Cancer Classification - You are looking at www.oncoprof.net website